WO2023233290 - RNAI AGENTS TARGETING PD-L1

National phase entry is expected:
Publication Number WO/2023/233290
Publication Date 07.12.2023
International Application No. PCT/IB2023/055528
International Filing Date 30.05.2023
Title **
[English] RNAI AGENTS TARGETING PD-L1
[French] AGENTS D'ARNI CIBLANT PD-L1
Applicants **
JANSSEN SCIENCES IRELAND UNLIMITED COMPANY Barnahely Ringaskiddy Co Cork, IE
Inventors
JIN, Yi c/o Janssen Research & Development, LLC 920 US Route 202 PO Box 300 Raritan, New Jersey 08869, US
VAN GULCK, Ellen Rosalie A c/o Janssen Pharmaceutica NV Turnhoutseweg 30 2340 Beerse, BE
OLLMANN, Michael Martin c/o Janssen Research & Development, LLC 920 US Route 202 PO Box 300 Raritan, New Jersey 08869, US
RAMASESHAN, Mahesh c/o Janssen Research & Development, LLC 920 US Route 202 PO Box 300 Raritan, New Jersey 08869, US
Priority Data
63/365,533   31.05.2022   US
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Quotation for National Phase entry

Country StagesTotal
China Filing2975
EPO Filing, Examination17188
Japan Filing529
South Korea Filing575
USA Filing, Examination10535
MasterCard Visa

Total: 31802

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] Described are RNA interference (RNAi) agents for inhibiting the expression of PD-L1, and compositions comprising the RNAi agents and methods of administering same. The RNAi agents are useful in the treatment of diseases, such as, for example, HBV infection, HDV infection, and/or cancer, more particularly chronic HBV infection.[French] L'invention concerne des agents d'interférence ARN (ARNi) pour inhiber l'expression de PD-L1, et des compositions comprenant les agents d'ARNi et des procédés d'administration de ceux-ci. Les agents d'ARNi sont utiles dans le traitement de maladies, telles que, par exemple, une infection par le VHB, une infection par le VHD et/ou un cancer, plus particulièrement une infection chronique par le VHB.
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