Publication Number
WO/2024/079623
Publication Date
18.04.2024
International Application No.
PCT/IB2023/060166
International Filing Date
10.10.2023
Title
[English]
TRICYCLIC COMPOUNDS AND THEIR USES
[French]
COMPOSÉS TRICYCLIQUES ET LEURS UTILISATIONS
Applicants **
NOVARTIS AG
Lichtstrasse 35
4056 Basel, CH
Inventors **
BORDAS, Vincent
c/o Novartis Pharma AG
Lichtstrasse 35
4056 Basel, CH
FUREGATI, Markus
c/o Novartis Pharma AG
Lichtstrasse 35
4056 Basel, CH
HAMON, Jacques
c/o Novartis Pharma AG
Lichtstrasse 35
4056 Basel, CH
HINRICHS, Juergen Hans-Hermann
c/o Novartis Pharma AG
Lichtstrasse 35
4056 Basel, CH
HONG, Ziyue
China Novartis Inst for Biomedical Research Co Ltd.,
4218 Jinke Road
Pudong New Area, Shanghai 201203, CN
LIMA, Fabio
c/o Novartis Pharma AG
Lichtstrasse 35
4056 Basel, CH
LIMAM, Fatma
c/o Novartis Pharma AG
Lichtstrasse 35
4056 Basel, CH
MOEBITZ, Henrik
c/o Novartis Pharma AG
Lichtstrasse 35
4056 Basel, CH
NOCITO, Sandro
c/o Novartis Pharma AG
Lichtstrasse 35
4056 Basel, CH
SCHMIEDEBERG, Niko
c/o Novartis Pharma AG
Lichtstrasse 35
4056 Basel, CH
SCHOEPFER, Joseph
c/o Novartis Pharma AG
Lichtstrasse 35
4056 Basel, CH
STRANG, Ross
c/o Novartis Pharma AG
Lichtstrasse 35
4056 Basel, CH
ZECRI, Frederic
c/o Novartis Institutes for BioMedical Research, Inc.
250 Massachusetts Avenue
Cambridge, Massachusetts 02139, US
YU, Huangchao
Suzhou Novartis Technical Development Co., Ltd., #18-1, Tonglian Road, Bixi Subdistrict
Changshu, Jiangsu 215537, CN
ZHANG, Yong
Suzhou Novartis Technical Development Co., Ltd., #18-1, Tonglian Road, Bixi Subdistrict
Changshu, Jiangsu 215537, CN
YANG, Xinkan
Suzhou Novartis Technical Development Co., Ltd., #18-1, Tonglian Road, Bixi Subdistrict
Changshu, Jiangsu 215537, CN
ZHANG, Sisi
Suzhou Novartis Technical Development Co., Ltd., #18-1, Tonglian Road, Bixi Subdistrict
Changshu, Jiangsu 215537, CN
LI, Wei
Suzhou Novartis Technical Development Co., Ltd., #18-1, Tonglian Road, Bixi Subdistrict
Changshu, Jiangsu 215537, CN
Priority Data
PCT/CN2022/124865
 12.10.2022
 CN
22208192.9
 17.11.2022
 EP
63/494,033
 04.04.2023
 US
PCT/CN2023/108913
 24.07.2023
 CN
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Abstract
[English]
, y, R, M, W, L, V, T, Y, J, K and A are as described herein, therapeutic uses of said compounds, uses of said compounds as research chemicals, a pharmaceutical composition and combinations comprising said compounds, and methods for manufacturing the compounds of the invention.
[French]
, y, R, M, W, L, V, T, Y, J, K et A sont tels que décrits dans la description, des utilisations thérapeutiques desdits composés, des utilisations desdits composés en tant que produits chimiques de recherche, une composition pharmaceutique et des combinaisons comprenant lesdits composés, et des procédés de fabrication des composés de l'invention.