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WO2025104695 - IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES THEREOF

National phase entry is expected:
Publication Number WO/2025/104695
Publication Date 22.05.2025
International Application No. PCT/IB2024/061417
International Filing Date 15.11.2024
Title [English] IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES THEREOF [French] LIPIDES CATIONIQUES IONISABLES ET NANOPARTICULES LIPIDIQUES ASSOCIÉES
Applicants ** CORTI THERAPEUTICS PTE. LTD. 120 Lower Delta Road #10-09 Cendex Centre Singapore 169208, SG
Inventors ** HU, Qi-Ying c/o Corti Therapeutics PTE. LTD. 120 Lower Delta Road #10-09 Cendex Centre Singapore 169208, SG
Priority Data 63/599,781  16.11.2023  US 63/693,874  12.09.2024  US
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Quotation for National Phase entry

Country Stages Total
China Filing 2665
EPO Filing, Examination 12760
Japan Filing 554
South Korea Filing 611
USA Filing, Examination 6135
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Abstract [English] ) are as described herein. Also provided are lipid nanoparticles comprising ionizable lipids of Formula (I), or a pharmaceutically acceptable salt, solvate, or hydrate thereof, and methods of using the ionizable lipids, e.g., to administer therapy to a subject in need thereof. [French] ) sont tels que décrits dans la description. L'invention concerne également des nanoparticules lipidiques comprenant des lipides ionisables de formule (I), ou un sel, un solvate ou un hydrate pharmaceutiquement acceptable de ceux-ci, et des procédés d'utilisation des lipides ionisables, par exemple, pour administrer une thérapie à un sujet en ayant besoin.